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DeCS
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Descriptor English:
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Parkinson Disease
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Descriptor Spanish:
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Enfermedad de Parkinson
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Descriptor Portuguese:
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Doença de Parkinson
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Synonyms English:
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Idiopathic Parkinson Disease
Idiopathic Parkinson's Disease
Lewy Body Parkinson Disease
Lewy Body Parkinson's Disease
Paralysis Agitans
Parkinson Disease, Idiopathic
Parkinson's Disease
Parkinson's Disease, Idiopathic
Parkinson's Disease, Lewy Body
Parkinsonism, Primary
Primary Parkinsonism
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Tree Number:
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C10.228.140.079.862.500
C10.228.662.600.400
C10.574.928.750
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Definition English:
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A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) |
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Indexing Annotation English:
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drug ther: consider also ANTIPARKINSON AGENTS; /chem ind = PARKINSON DISEASE, SECONDARY/chem ind
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Entry Combination - descr/qualif English:
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Parkinson Disease/chemically induced use Parkinson Disease, Secondary/chemically induced
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See Related English:
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Lewy Bodies
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History Note English:
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1979(1963)
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Allowable Qualifiers English:
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Record Number:
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10489
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Unique Identifier:
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D010300
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Occurrence in VHL:
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Similar:
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DeCS
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